The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases. Currently, whether and how oligomerization impacts their biochemical and biological functions is not well understood. In this work,...

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Bibliografski detalji
Izdano u:iScience
Glavni autori: Marcaida, Maria J., Kauzlaric, Annamaria, Duperrex, Alice, Sülzle, Jenny, Moncrieffe, Martin C., Adebajo, Damilola, Manley, Suliana, Trono, Didier, Dal Peraro, Matteo
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721647/
https://ncbi.nlm.nih.gov/pubmed/33313488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101811
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