The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases. Currently, whether and how oligomerization impacts their biochemical and biological functions is not well understood. In this work,...

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Publicado no:iScience
Main Authors: Marcaida, Maria J., Kauzlaric, Annamaria, Duperrex, Alice, Sülzle, Jenny, Moncrieffe, Martin C., Adebajo, Damilola, Manley, Suliana, Trono, Didier, Dal Peraro, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721647/
https://ncbi.nlm.nih.gov/pubmed/33313488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101811
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