Increased Sirt1 secreted from visceral white adipose tissue is associated with improved glucose tolerance in obese Nrf2-deficient mice

Obesity is associated with metabolic dysregulation characterized by insulin resistance and glucose intolerance. Nuclear factor E2-related factor (Nrf2) is a critical regulator of the stress response and Nrf2-deficient mice (Nrf2(−/−)) are protected against high fat diet (HFD)-induced metabolic deran...

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發表在:Redox Biol
Main Authors: Braud, Laura, Pini, Maria, Stec, Donald F., Manin, Sylvie, Derumeaux, Geneviève, Stec, David E., Foresti, Roberta, Motterlini, Roberto
格式: Artigo
語言:Inglês
出版: Elsevier 2020
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721645/
https://ncbi.nlm.nih.gov/pubmed/33285413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101805
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