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Nivolumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use

PURPOSE: Cetuximab, which modulates immune responses, may affect the efficacy of subsequent immunotherapy. Here, we assessed outcomes with nivolumab, by prior cetuximab exposure, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) who had experienced p...

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Publicado en:Clin Cancer Res
Autores principales: Ferris, Robert L., Licitra, Lisa, Fayette, Jerome, Even, Caroline, Blumenschein, George, Harrington, Kevin J., Guigay, Joel, Vokes, Everett E., Saba, Nabil F., Haddad, Robert, Ramkumar, Shanmugasundaram, Russell, Jeffery, Brossart, Peter, Tahara, Makoto, Colevas, A. Dimitrios, Concha-Benavente, Fernando, Lynch, Mark, Li, Li, Gillison, Maura L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721346/
https://ncbi.nlm.nih.gov/pubmed/31239321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3944
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