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Dose-dependent effects of necrostatin-1 supplementation to tissue culture media of young porcine islets

Previous studies have shown that necrostatin-1 (Nec-1) supplementation improved the viability of murine islets following exposure to nitric oxide, increased the survival of human islets during hypoxic culture, and augmented the maturation of pre-weaned porcine islets (PPIs) after 7 days of tissue cu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lau, Hien, Corrales, Nicole, Rodriguez, Samuel, Luong, Colleen, Mohammadi, Mohammadreza, Khosrawipour, Veria, Li, Shiri, Alexander, Michael, de Vos, Paul, Lakey, Jonathan R. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721208/
https://ncbi.nlm.nih.gov/pubmed/33284818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243506
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