Pathophysiology and potential future therapeutic targets using preclinical models of COVID-19

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) gains entry into the lung epithelial cells by binding to the surface protein angiotensin-converting enzyme 2. Severe SARS-CoV-2 infection, also known as coronavirus disease 2019 (COVID-19), can lead to death due to acute respiratory distre...

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Bibliographic Details
Published in:ERJ Open Res
Main Authors: Kumar, Rahul, Lee, Michael H., Mickael, Claudia, Kassa, Biruk, Pasha, Qadar, Tuder, Rubin, Graham, Brian
Format: Artigo
Language:Inglês
Published: European Respiratory Society 2020
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720688/
https://ncbi.nlm.nih.gov/pubmed/33313306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00405-2020
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