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Hyaluronic acid-coated polymeric micelles with hydrogen peroxide scavenging to encapsulate statins for alleviating atherosclerosis

Inflammation and oxidative stress are two major factors that are involved in the pathogenesis of atherosclerosis. A smart drug delivery system that responds to the oxidative microenvironment of atherosclerotic plaques was constructed in the present study. Simvastatin (SIM)-loaded biodegradable polym...

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Détails bibliographiques
Publié dans:J Nanobiotechnology
Auteurs principaux: Mu, Dan, Li, Jianhui, Qi, Yu, Sun, Xuan, Liu, Yihai, Shen, Song, Li, Yuyu, Xu, Biao, Zhang, Bing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720571/
https://ncbi.nlm.nih.gov/pubmed/33287831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00744-w
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