Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome

BACKGROUND: It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in granulosa cells (GCs) of patients with...

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Detaylı Bibliyografya
Yayımlandı:Reprod Biol Endocrinol
Asıl Yazarlar: Gong, Yan, Luo, Shan, Fan, Ping, Zhu, Huili, Li, Yujing, Huang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720521/
https://ncbi.nlm.nih.gov/pubmed/33287836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-020-00677-x
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