Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms

BACKGROUND: Fluoropyrimidines and platinum are still widely used for colorectal cancer (CRC) management. Several studies have reported that mutations of dihydropyrimidine dehydrogenase (DPYD) and glutathione S-transferase pi-1 (GSTP1) polymorphisms are related to chemotherapy-related adverse events....

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Bibliografische gegevens
Gepubliceerd in:World J Surg Oncol
Hoofdauteurs: Deng, Xunwei, Hou, Jingyuan, Deng, Qiaoting, Zhong, Zhixiong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720377/
https://ncbi.nlm.nih.gov/pubmed/33280607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-020-02103-3
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