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Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA

The DNA polymerase (Pol) δ of Saccharomyces cerevisiae (S.c.) is composed of the catalytic subunit Pol3 along with two regulatory subunits, Pol31 and Pol32. Pol δ binds to proliferating cell nuclear antigen (PCNA) and functions in genome replication, repair, and recombination. Unique among DNA polym...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720213/
https://ncbi.nlm.nih.gov/pubmed/33203675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017637117
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