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Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA

The DNA polymerase (Pol) δ of Saccharomyces cerevisiae (S.c.) is composed of the catalytic subunit Pol3 along with two regulatory subunits, Pol31 and Pol32. Pol δ binds to proliferating cell nuclear antigen (PCNA) and functions in genome replication, repair, and recombination. Unique among DNA polym...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720213/
https://ncbi.nlm.nih.gov/pubmed/33203675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017637117
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