Randomised clinical study: oral aspirin 325 mg daily vs placebo alters gut microbial composition and bacterial taxa associated with colorectal cancer risk

BACKGROUND: Aspirin is associated with decreased risk of colorectal cancer (CRC), potentially by modulating the gut microbiome. AIM: To evaluate the effect of aspirin on the gut microbiome in a double-blinded, randomised placebo-controlled pilot trial. METHODS: Healthy volunteers aged 50-75 received...

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Detalhes bibliográficos
Publicado no:Aliment Pharmacol Ther
Main Authors: Prizment, Anna E., Staley, Christopher, Onyeaghala, Guillaume C., Vivek, Sithara, Thyagarajan, Bharat, Straka, Robert J., Demmer, Ryan T., Knights, Dan, Meyer, Katie A., Shaukat, Aasma, Sadowsky, Michael J., Church, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719064/
https://ncbi.nlm.nih.gov/pubmed/32770859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.16013
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