Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis

Overactivation of microglia is associated with most neurodegenerative diseases. In this study we examined whether PET-measurable innate immune cell activation predicts multiple sclerosis disease progression. Activation of microglia/macrophages was measured using the 18-kDa translocator protein (TSPO...

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Publicat a:Brain
Autors principals: Sucksdorff, Marcus, Matilainen, Markus, Tuisku, Jouni, Polvinen, Eero, Vuorimaa, Anna, Rokka, Johanna, Nylund, Marjo, Rissanen, Eero, Airas, Laura
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719021/
https://ncbi.nlm.nih.gov/pubmed/33006604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa275
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