Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia

Aurora kinases (AURKA and AURKB) are mitotic kinases with an important role in the regulation of several mitotic events, and in hematological malignancies, AURKA and AURKB hyperexpression are found in patients with cytogenetic abnormalities presenting a unfavorable prognosis. The aim of this study w...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Moreira-Nunes, Caroline Aquino, Mesquita, Felipe Pantoja, Portilho, Adrhyann Jullyanne de Sousa, Mello Júnior, Fernando Augusto Rodrigues, Maués, Jersey Heitor da Silva, Pantoja, Laudreísa da Costa, Wanderley, Alayde Vieira, Khayat, André Salim, Zuercher, William J., Montenegro, Raquel Carvalho, de Moraes-Filho, Manoel Odorico, de Moraes, Maria Elisabete Amaral
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718893/
https://ncbi.nlm.nih.gov/pubmed/33277547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78024-8
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