Multimerization of Zika Virus-NS5 causes ciliopathy and forces premature neurogenesis

Zika virus (ZikV) is a flavivirus that infects neural tissues, causing congenital microcephaly. ZikV has evolved multiple mechanisms to restrict proliferation and enhance cell death, although the underlying cellular events involved remain unclear. Here we show that the ZikV-NS5 protein interacts wit...

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Publicado en:Cell Stem Cell
Main Authors: Saade, Murielle, Ferrero, Diego S, Blanco-Ameijeiras, José, Gonzalez-Gobartt, Elena, Flores-Mendez, Marco, Ruiz-Arroyo, Victor M, Martínez-Sáez, Elena, Cajal, Santiago Ramón y, Akizu, Naiara, Verdaguer, Nuria, Martí, Elisa
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718408/
https://ncbi.nlm.nih.gov/pubmed/33147489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.10.002
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