Functional precision medicine identifies new therapeutic candidates for medulloblastoma

Medulloblastoma (MB) is among the most common malignant brain tumors in children. Recent studies have identified at least four subgroups of the disease that differ in terms of molecular characteristics and patient outcomes. Despite this heterogeneity, most MB patients receive similar therapies, incl...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Rusert, Jessica M., Juarez, Edwin F., Brabetz, Sebastian, Jensen, James, Garancher, Alexandra, Chau, Lianne Q., Tacheva-Grigorova, Silvia K., Wahab, Sameerah, Udaka, Yoko T., Finlay, Darren, Seker-Cin, Huriye, Reardon, Brendan, Gröbner, Susanne, Serrano, Jonathan, Ecker, Jonas, Qi, Lin, Kogiso, Mari, Du, Yuchen, Baxter, Patricia A., Henderson, Jacob J., Berens, Michael E., Vuori, Kristiina, Milde, Till, Cho, Yoon-Jae, Li, Xiao-Nan, Olson, James M., Reyes, Iris, Snuderl, Matija, Wong, Terence C., Dimmock, David P., Nahas, Shareef A., Malicki, Denise, Crawford, John R., Levy, Michael L., Van Allen, Eliezer M., Pfister, Stefan M., Tamayo, Pablo, Kool, Marcel, Mesirov, Jill P., Wechsler-Reya, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718387/
https://ncbi.nlm.nih.gov/pubmed/33046443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1655
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