Divergent Effects of Systemic and Intracollicular CB Receptor Activation Against Forebrain and Hindbrain-Evoked Seizures in Rats

Cannabinoid (CB) receptor agonists are of growing interest as targets for anti-seizure therapies. Here we examined the effect of systemic administration of the CB receptor agonist WIN 55,212-2 (WIN) against audiogenic seizures (AGSs) in the Genetically Epilepsy Prone Rat (GEPR)-3 strain, and against...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Santos, Victor R., Hammack, Robert, Wicker, Evan, N’Gouemo, Prosper, Forcelli, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Behavioral Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718031/
https://ncbi.nlm.nih.gov/pubmed/33328922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2020.595315
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