A randomized, multi-center, open-label study to compare the safety and efficacy between afatinib monotherapy and combination therapy of afatinib and HAD-B1 for the locally advanced or metastatic NSCLC patients with EGFR mutations

BACKGROUND: Afatinib is an epidermal growth factor receptor - tyrosine kinase inhibitor (EGFR-TKI) with proven efficacy for treating patients with advanced or metastatic non-small cell lung cancer (NSCLC). Unfortunately, responses are limited by acquired resistance. Because traditional Korean medici...

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Dades bibliogràfiques
Publicat a:Medicine (Baltimore)
Autors principals: Song, Si-Yeon, Ha, Su-Jeong, Park, Ji-Hye, Park, So-Jung, Shin, Seong Hoon, Oak, Chulho, Choi, Jun-Yong, Yoon, Seong Woo, Kim, Jung-A, Yoon, Seong Hoon, Son, Ji Woong, Kim, Seung Joon, Yoo, Hwa-Seung
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
Matèries:
5700
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717758/
https://ncbi.nlm.nih.gov/pubmed/33285743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000023455
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