Sources of off-target effects of vagus nerve stimulation using the helical clinical lead in domestic pigs

OBJECTIVE. Clinical data suggest that efficacious vagus nerve stimulation (VNS) is limited by side effects such as cough and dyspnea that have stimulation thresholds lower than those for therapeutic outcomes. VNS side effects are putatively caused by activation of nearby muscles within the neck, via...

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Pubblicato in:J Neural Eng
Autori principali: Nicolai, Evan N, Settell, Megan L, Knudsen, Bruce E, McConico, Andrea L, Gosink, Brian A, Trevathan, James K, Baumgart, Ian W, Ross, Erika K, Pelot, Nicole A, Grill, Warren M, Gustafson, Kenneth J, Shoffstall, Andrew J, Williams, Justin C, Ludwig, Kip A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717671/
https://ncbi.nlm.nih.gov/pubmed/32554888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1741-2552/ab9db8
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