SARS-CoV-2 triggering severe ARDS and secondary HLH in a 3-year-old child with Down syndrome

Down syndrome (DS) predisposes to severe immunologic reaction secondary to infectious triggers. Here we report a paediatric DS patient with COVID-19 who developed a hyperinflammatory syndrome, severe ARDS and secondary HLH requiring PICU admission and treatment with steroids, IVIG and Remdesivir. In...

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Detalhes bibliográficos
Publicado no:J Pediatric Infect Dis Soc
Main Authors: Kim-Hellmuth, Sarah, Hermann, Matthias, Eilenberger, Julia, Ley-Zaporozhan, Julia, Fischer, Marcus, Hauck, Fabian, Klein, Christoph, Haas, Nikolaus, Kappler, Matthias, Huebner, Johannes, Jakob, André, von Both, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717321/
https://ncbi.nlm.nih.gov/pubmed/33188394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jpids/piaa148
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