Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers

BACKGROUND: As the causative agent of COVID-19, SARS-CoV-2 is a pathogen of immense importance to global public health. Development of innovative direct-acting antiviral agents is sorely needed to address this virus. Peptide-conjugated morpholino oligomers (PPMO) are antisense compounds composed of...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Rosenke, Kyle, Leventhal, Shanna, Moulton, Hong M, Hatlevig, Susan, Hawman, David, Feldmann, Heinz, Stein, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717290/
https://ncbi.nlm.nih.gov/pubmed/33164048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa460
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