Analysis of Pre- and Posttreatment Tissues from the SWOG S0800 Trial Reveals an Effect of Neoadjuvant Chemotherapy on the Breast Cancer Genome

PURPOSE: We performed whole exome sequencing of pre- and post-treatment cancer tissues to assess the somatic mutation landscape of tumors before and after neoadjuvant taxane and anthracycline chemotherapy with or without bevacizumab. EXPERIMENTAL DESIGN: 29 pre-treatment biopsies from the SWOG S0800...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Powles, Ryan L., Wali, Vikram B., Li, Xiaotong, Barlow, William E., Nahleh, Zeina A., Thompson, Alastair, Godwin, Andrew K., Hatzis, Christos, Pusztai, Lajos
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717064/
https://ncbi.nlm.nih.gov/pubmed/31919134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2405
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