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Compromised barrier integrity of human feto-placental vessels from gestational diabetic pregnancies is related to downregulation of occludin expression

AIMS/HYPOTHESIS: Reduced occupancy of junctional occludin is a feature of human placental vessels in the diabetic milieu. However, the functional consequence of this and whether this loss is due to differential expression of occludin splice variants is not known. Our study aimed to investigate the e...

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Publicado en:Diabetologia
Main Authors: Villota, Stephany Daniela, Toledo-Rodriguez, Maria, Leach, Lopa
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716932/
https://ncbi.nlm.nih.gov/pubmed/33001231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05290-6
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