Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Small-cell lung cancer (SCLC) is a highly aggressive cancer with poor prognosis, due to a lack of therapeutic targets. Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables and has shown anticancer effects against numerous types of cancer. However, its anticancer effect against...

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Gepubliceerd in:Oncol Lett
Hoofdauteurs: Iida, Yuko, Okamoto-Katsuyama, Mayumi, Maruoka, Shuichiro, Mizumura, Kenji, Shimizu, Tetsuo, Shikano, Sotaro, Hikichi, Mari, Takahashi, Mai, Tsuya, Kota, Okamoto, Shinichi, Inoue, Toshio, Nakanishi, Yoko, Takahashi, Noriaki, Masuda, Shinobu, Hashimoto, Shu, Gon, Yasuhiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2021
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716721/
https://ncbi.nlm.nih.gov/pubmed/33365082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12332
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