shp-2 gene knockout upregulates CAR-driven cytotoxicity of YT NK cells

In Russia, cancer is the second leading cause of death following cardiovascular diseases. Adoptive transfer of NK cells is a promising approach to fight cancer; however, for their successful use in cancer treatment, it is necessary to ensure their robust accumulation at tumor foci, provide resistanc...

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Bibliografiske detaljer
Udgivet i:Vavilovskii Zhurnal Genet Selektsii
Main Authors: Subrakova, V.G., Kulemzin, S.V., Belovezhets, T.N., Chikaev, A.N., Chikaev, N.A., Koval, O.A., Gorchakov, A.A., Taranin, A.V.
Format: Artigo
Sprog:Inglês
Udgivet: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716529/
https://ncbi.nlm.nih.gov/pubmed/33659784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18699/VJ20.598
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