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Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility

BACKGROUND: The efficacy of mesenchymal stromal cell (MSC) therapy is thought to depend on the intrinsic heterogeneity of MSC cultures isolated from different tissue sources as well as individual MSCs isolated from the same tissue source, neither of which is well understood. To study this, we used M...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Harman, Rebecca M., Patel, Roosheel S., Fan, Jennifer C., Park, Jee E., Rosenberg, Brad R., Van de Walle, Gerlinde R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716481/
https://ncbi.nlm.nih.gov/pubmed/33276815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02043-5
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