Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer

BACKGROUND: Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify later risk, have not been determined. The study aimed to investigate the impact...

詳細記述

保存先:
書誌詳細
出版年:BMC Med
主要な著者: Tharmalingam, Melissa D., Matilionyte, Gabriele, Wallace, William H. B., Stukenborg, Jan-Bernd, Jahnukainen, Kirsi, Oliver, Elizabeth, Goriely, Anne, Lane, Sheila, Guo, Jingtao, Cairns, Bradley, Jorgensen, Anne, Allen, Caroline M., Lopes, Federica, Anderson, Richard A., Spears, Norah, Mitchell, Rod T.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716476/
https://ncbi.nlm.nih.gov/pubmed/33272271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01844-y
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