Genetic alterations and expression characteristics of ARID1A impact tumor immune contexture and survival in early-onset gastric cancer

The AT-rich Interactive Domain 1A (ARID1A) is one of the most frequently mutated genes in gastric cancer. Here, we found that genetic variants in noncoding regions of ARID1A associated with altered protein levels by target sequencing. Notably, tumors with ARID1A variants in the 3’untranslated region...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Zou, Jun, Qin, Wan, Yang, Lin, Wang, Lulu, Wang, Yu, Shen, Jianfeng, Xiong, Wei, Yu, Shiying, Song, Shumei, Ajani, Jaffer A, Lin, Shiaw-Yih, Mills, Gordon B, Yuan, Xianglin, Chen, Jianying, Peng, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716160/
https://ncbi.nlm.nih.gov/pubmed/33294279
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