Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD

Mitochondrial adaptation during non-alcoholic fatty liver disease (NAFLD) include remodeling of ketogenic flux and sustained tricarboxylic acid (TCA) cycle activity, which are concurrent to onset of oxidative stress. Over 70% of obese humans have NAFLD and ketogenic diets are common weight loss stra...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Muyyarikkandy, Muhammed S., McLeod, Marc, Maguire, Meghan, Mahar, Rohit, Kattapuram, Nathan, Zhang, Christine, Surugihalli, Chaitra, Muralidaran, Vaishna, Vavilikolanu, Kruthi, Mathews, Clayton E., Merritt, Matthew E., Sunny, Nishanth E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716091/
https://ncbi.nlm.nih.gov/pubmed/32918763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001495R
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