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Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

4-Aminopyridine (4-AP), an FDA-approved drug for the symptomatic treatment of multiple sclerosis, is used to improve neuromuscular function in patients with diverse demyelinating disorders. We recently demonstrated that local, transdermal or injectable forms of 4-AP improve myelination, nerve conduc...

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Detalhes bibliográficos
Publicado no:Neural Regen Res
Main Authors: Hsu, Chia George, Talukder, M A Hassan, Yue, Li, Turpin, Loel C., Noble, Mark, Elfar, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716044/
https://ncbi.nlm.nih.gov/pubmed/32394968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.280319
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