EPEN-28. NOVEL ONCOGENE AMPLIFICATION IN SPINAL EPENDYMOMA INVOLVING THE MYC LOCUS (8q24)

BACKGROUND: We report a unique case of spinal ependymoma with classic histology and aggressive clinical behavior which harbored a focal MYC (8q24) amplification. CASE REPORT: A-12-year old male presented with a three months history of back pain and acute onset weakness with ataxia. A spine MRI revea...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Shatara, Margaret, Boué, Daniel R, Pierson, Christopher R, Thomas, Diana L, Sribnick, Eric A, Jones, Jeremy, Rodriguez, Diana P, Schieffer, Kathleen M, Deeg, Carol, Hamelberg, Elizabeth, LaHaye, Stephanie, Magrini, Vincent, Wilson, Richard K, Mardis, Elaine R, Cottrell, Catherine E, Varga, Elizabeth A, AbdelBaki, Mohamed S, Finlay, Jonathan L, Osorio, Diana S
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Ependymoma
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715824/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.165
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