HGG-48. ROS1 INHIBITOR ENTRECTINIB USE IN RELAPSE/REFRACTORY INFANTILE GLIOBLASTOMA WITH POSITIVE ROS1 FUSION - A CASE REPORT WITH PROMISING RESPONSE

INTRODUCTION: Infantile glioblastoma is rare with poor prognosis. Recent molecular study for infantile hemispheric high grade glioma found its association with ALK/ROS1/NTRK/MET pathway. This suggested the potential use of targeted therapy for refractory / relapse patients. CASE: A newborn presented...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ku, Dennis Tak-Loi, Shing, Matthew Ming-Kong, Chan, Godfrey Chi-Fung, Fu, Eric, Yau, Ping-Wa, Luk, Chung-Wing, Cheng, King-Fai, Ho, Wilson Wai-Shing, Ng, Ho-Keung, Po, Yin-Chung, Ling, Alvin Siu-Cheung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
High Grade Glioma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715712/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.328
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