IMMU-02. CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL NEUROTOXICITY CORRELATES WITH PRETREATMENT AND ACUTE CSF NEUROFILAMENT LIGHT CHAIN (NFL) LEVELS

OBJECTIVE: Immunotherapy for hematologic malignancies with CD19-directed CAR T cells is complicated by neurotoxicity in approximately 40% of patients. We have previously reported evidence of glial injury in pediatric patients with CAR T neurotoxicity by elevated CSF levels of GFAP and S100b. We now...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Gust, Juliane, Wilson, Ashley, Finney, Olivia, Hartsuyker, Kendra Jae, Narayanaswamy, Prabha, Wu, Vicky, Garden, Gwenn, Annesley, Colleen, Gardner, Rebecca
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Immunotherapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715669/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.359
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars