MBCL-25. PILOT STUDY OF A SURGERY AND CHEMOTHERAPY-ONLY APPROACH IN THE UPFRONT THERAPY OF CHILDREN WITH WNT-POSITIVE STANDARD RISK MEDULLOBLASTOMA: UPDATED OUTCOMES

BACKGROUND: Wnt+ medulloblastoma (WPM) is a favorable subtype with EFS > 90% when treating postoperatively with craniospinal irradiation and posterior fossa boost (CSI/XRT) followed by adjuvant chemotherapy. This pilot study explored the safety of omitting radiation in standard-risk WPM. METHODS:...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Cohen, Kenneth, Chi, Susan, Hawkins, Cynthia, Rodriguez, Fausto, London, Wendy, Castellino, Robert Craig, Aguilera, Dolly, Stapleton, Stacie, Ashley, David, Landi, Daniel, Bandopadhayay, Pratiti
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Medulloblastoma (Clinical)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715534/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.501
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