EPEN-25. EXCEPTIONAL CLINICAL AND IMAGING RESPONSE TO TRK-INHIBITION IN A PATIENT WITH SUPRATENTORIAL EPENDYMOMA HARBORING NTRK2 GENE FUSION

BACKGROUND: Patients with metastatic pediatric ependymoma have limited therapeutic options and poor outcomes. Approximately ¾ of supratentorial ependymomas are driven by C11ORF95-RELA fusions, and the remaining by a heterogeneous group of fusion events. We present a six year-old male diagnosed with...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Mangum, Ross, Reuther, Jacquelyn, Adesina, Adekunle, Kukreja, Marcia, Curry, Daniel, Malbari, Fatema, Chintagumpala, Murali, Muzny, Donna M, Fisher, Kevin, Roy, Angshumoy, Bertrand, Kelsey C, Mack, Stephen C, Plon, Sharon E, Parsons, D Williams, Lin, Frank Y
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Ependymoma
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715314/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.162
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