MBCL-46. TREATMENT OF RECURRENT WINGLESS-ACTIVATED MEDULLOBLASTOMA (Wnt-MB) INCORPORATING MARROW-ABLATIVE THIOTEPA AND CARBOPLATIN CHEMOTHERAPY (HDCx) AND AUTOLOGOUS HEMATOPOIETIC PROGENITOR CELL RESCUE (AuHPCR): A DUAL REPORT

BACKGROUND: Wnt-MB infers an excellent prognosis, and metastatic disease is rare. However, specific treatment strategies and patterns of failure for patients with recurrent Wnt-MB are unknown. We report two cases of recurrent beta-catenin nucleopositive Wnt-MBs treated with an irradiation-sparing st...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Harris, Micah K, Funk, Zachary N, Boué, Daniel R, Pierson, Christopher R, Jones, Jeremy, Leonard, Jeffrey, Abu-Arja, Rolla, Auletta, Jeffrey, Osorio, Diana S, Shatara, Margaret, Paul, Stephan R, Finlay, Jonathan L, AbdelBaki, Mohamed S
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Medulloblastoma (Clinical)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715265/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.517
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