EPEN-27. CDKN2A DELETION IN SUPRATENTORIAL EPENDYMOMA WITH RELA ALTERATION INDICATES A DISMAL PROGNOSIS – A RETROSPECTIVE ANALYSIS OF THE HIT EPENDYMOMA TRIAL COHORT

INTRODUCTION: Since supratentorial RELA-fusion positive ependymomas are considered a biologically distinct disease, we aimed to identify histological and genetic predictors of outcome in a defined cohort of pediatric patients. MATERIALS AND METHODS: We analyzed 54 RELA ependymomas in pediatric patie...

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Publicat a:Neuro Oncol
Autors principals: Jünger, Stephanie T, Andreiuolo, Felipe, Mynarek, Martin, Dörner, Evelyn, zur Mühlen, Anja, Velez-Char, Natalia, von Hoff, Katja, Rutkowski, Stefan, Warmuth-Metz, Monika, Kortmann, Rolf-Dieter, Timmermann, Beate, von Bueren, Andre O, Pietsch, Torsten
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Ependymoma
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.164
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