HGG-20. DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS

Replication repair deficiency (RRD) is an important driving mechanism of pediatric high grade glioma (pHGG) occurring predominantly in the context of germline mutations in RRD-associated genes. Although pHGG present specific patterns of DNA methylation corresponding to driving oncogenic processes, m...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Dodgshun, Andrew, Fukuoka, Kohei, Edwards, Melissa, Bianchi, Vanessa, Sexton-Oates, Alexandra, Larouche, Valerie, Magimairajan, Vanan, Lindhorst, Scott, Yalon, Michal, Mason, Gary, Crooks, Bruce, Constantini, Shlomi, Massimino, Maura, Chiaravalli, Stefano, Ramdas, Jagadeesh, Mason, Warren, Shamvil, Ashraf, Farah, Roula, Van Damme, An, Opocher, Enrico, Hamid, Syed Ahmer, Ziegler, David, Samuel, David, Cole, Kristina A, Tomboc, Patrick, Stearns, Duncan, Thomas, Gregory, Lossos, Alexander, Sullivan, Michael, Hansford, Jordan R, Jones, David, Mackay, Alan, Jones, Chris, Ramaswamy, Vijay, Hawkins, Cynthia, Bouffet, Eric, Tabori, Uri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
High Grade Glioma
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715189/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.307
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