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DDEL-14. SAFETY OF INTERVENTRICULAR METHOTREXATE ADMINISTRATION FOLLOWING RADIATION IN PEDIATRIC PATIENTS WITH MALIGNANT BRAIN TUMORS

BACKGROUND: Methotrexate has been used for intrathecal administration in leukemia as well as embryonal CNS tumors in children. Concerns about neurologic side effects including leukoencephalopathy, demyelination, and seizures have limited the use of methotrexate following exposure to focal radiation....

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rosales, Kristofer, Maher, Ossama, Fader, Maggie, Gallegos, Natalie, Niazi, Toba, Ragheb, John, Khatib, Ziad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715178/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.049
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