GCT-25. INNOVATIVE, INTENSIVE IRRADIATION-AVOIDING/MINIMIZING CHEMOTHERAPY FOR HIGH-RISK PRIMARY CENTRAL NERVOUS SYSTEM (CNS) MIXED MALIGNANT GERM CELL TUMORS (HR-MMGCT): A PILOT STUDY AND PROPOSED MULTI-NATIONAL PROSPECTIVE TRIAL

BACKGROUND: About one-third of children with primary CNS MMGCT experience incomplete responses to initial induction chemotherapy prior to irradiation, many of whom will subsequently relapse. Such high-risk patients are variably defined as having initial alpha-fetoprotein (AFP) elevations exceeding 1...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Finlay, Jonathan L, Abu-Arja, Mohammad H, Abu-Arja, Rolla, Auletta, Jeffery, AbdelBaki, Mohamed S, Osorio, Diana S, Conley, Suzanne, Shatara, Margaret, Boué, Daniel R, Pierson, Christopher R, Rusin, Jerome, Martin, Lisa, Jones, Jeremy, Palmer, Joshua D, Vatner, Ralph, Drapeau, Annie, Sribnick, Eric, Leonard, Jeffrey R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Germ Cell Tumors
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715075/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.245
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