MODL-12. DEVELOPMENT OF A NOVEL IMMUNOCOMPETENT MOUSE MODEL FOR DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is a devastating brain tumor affecting young children. Immunotherapies hold promise however the lack of immunocompetent models recreating a faithful tumor microenvironment (TME) remains a challenge for development of targeted immunotherapeutics. We propose to...

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Publicat a:Neuro Oncol
Autors principals: Seblani, Maggie, Zannikou, Markella, Pituch, Katarzyna, Ilut, Liliana, Becher, Oren, Balyasnikova, Irina
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Preclinical Models/Experimental Therapy/Drug Discovery
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715073/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.586
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