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Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy

Hypoxia is a serious impediment to current treatments of many malignant tumors. Catalase, an antioxidant enzyme, is capable of decomposing endogenous hydrogen peroxide (H(2)O(2)) into oxygen for tumor reoxygenation, but suffered from in vivo instability and limited delivery to deep interior hypoxic...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Yin, Junjing, Cao, Haiqiang, Wang, Hong, Sun, Kaoxiang, Li, Yaping, Zhang, Zhiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714984/
https://ncbi.nlm.nih.gov/pubmed/33304789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.06.004
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