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Ablation of IL33 suppresses Th2 responses, but with sustained mucus obstruction, in the Scnn1b transgenic mouse model
Cystic fibrosis (CF) is characterized by dehydration of the airway surface liquid (ASL) layer with persistent mucus obstruction. T-helper 2 (Th2) immune responses are often manifested as increased mucous cell density [mucous cell metaplasia (MCM)] associated with mucus obstruction. Interleukin 33 (I...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714586/ https://ncbi.nlm.nih.gov/pubmed/32060135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900234 |
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