Ablation of IL33 suppresses Th2 responses, but with sustained mucus obstruction, in the Scnn1b transgenic mouse model

Cystic fibrosis (CF) is characterized by dehydration of the airway surface liquid (ASL) layer with persistent mucus obstruction. T-helper 2 (Th2) immune responses are often manifested as increased mucous cell density [mucous cell metaplasia (MCM)] associated with mucus obstruction. Interleukin 33 (I...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Lewis, Brandon W, Vo, Thao, Choudhary, Ishita, Kidder, Allison, Bathula, Chandra, Ehre, Camille, Wakamatsu, Nobuko, Patial, Sonika, Saini, Yogesh
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714586/
https://ncbi.nlm.nih.gov/pubmed/32060135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900234
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