Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients

Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are found frequently in malignant gliomas and are likely involved in early gliomagenesis. To understand the prevalence of these mutations and their relationship to other genetic alterations and impact on prognosis for Japanese glioma patients,...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Mukasa, Akitake, Takayanagi, Shunsaku, Saito, Kuniaki, Shibahara, Junji, Tabei, Yusuke, Furuya, Kazuhide, Ide, Takafumi, Narita, Yoshitaka, Nishikawa, Ryo, Ueki, Keisuke, Saito, Nobuhito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713609/
https://ncbi.nlm.nih.gov/pubmed/22136423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02175.x
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