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A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors,

Olaparib (AZD2281) is an orally active Poly(ADP‐ribose) polymerase (PARP) inhibitor with favorable antitumor activity in advanced ovarian and breast cancers with BRCA1/2 mutations in Western (USA and European) studies. This Phase I dose‐finding study evaluated the tolerability, pharmacokinetics, PAR...

詳細記述

保存先:
書誌詳細
出版年:Cancer Sci
主要な著者: Yamamoto, Noboru, Nokihara, Hiroshi, Yamada, Yasuhide, Goto, Yasushi, Tanioka, Maki, Shibata, Takashi, Yamada, Kazuhiko, Asahina, Hajime, Kawata, Toshio, Shi, Xiaojin, Tamura, Tomohide
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713608/
https://ncbi.nlm.nih.gov/pubmed/22145984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02179.x
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