Bladder urothelium converts bacterial lipopolysaccharide information into neural signaling via an ATP-mediated pathway to enhance the micturition reflex for rapid defense

When bacteria enter the bladder lumen, a first-stage active defensive mechanism flushes them out. Although urinary frequency induced by bacterial cystitis is a well-known defensive response against bacteria, the underlying mechanism remains unclear. In this study, using a mouse model of acute bacter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ueda, Norichika, Kondo, Makoto, Takezawa, Kentaro, Kiuchi, Hiroshi, Sekii, Yosuke, Inagaki, Yusuke, Soda, Tetsuji, Fukuhara, Shinichiro, Fujita, Kazutoshi, Uemura, Motohide, Imamura, Ryoichi, Miyagawa, Yasushi, Nonomura, Norio, Shimada, Shoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713076/
https://ncbi.nlm.nih.gov/pubmed/33273625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78398-9
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