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Molecular Modeling of the Shigella flexneri Serogroup 3 and 5 O-Antigens and Conformational Relationships for a Vaccine Containing Serotypes 2a and 3a

The pathogenic bacterium Shigella flexneri is a leading global cause of diarrheal disease. The O-antigen is the primary vaccine target and distinguishes the 30 serotypes reported. Except for serotype 6, all S. flexneri serotypes have a common backbone repeating unit (serotype Y), with variations in...

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Dades bibliogràfiques
Publicat a:Vaccines (Basel)
Autors principals: Hlozek, Jason, Owen, Sara, Ravenscroft, Neil, Kuttel, Michelle M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712985/
https://ncbi.nlm.nih.gov/pubmed/33147882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040643
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