Primidone blocks RIPK1-driven cell death and inflammation

The receptor-interacting serine/threonine protein kinase 1 (RIPK1) is a key mediator of regulated cell death and inflammation. Recent studies suggest that RIPK1 inhibition would fundamentally improve the therapy of RIPK1-dependent organ damage in stroke, myocardial infarction, kidney failure, and sy...

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Publicado en:Cell Death Differ
Main Authors: Riebeling, Theresa, Jamal, Kunzah, Wilson, Rebecca, Kolbrink, Benedikt, von Samson-Himmelstjerna, Friedrich Alexander, Moerke, Caroline, Ramos Garcia, Laura, Dahlke, Eileen, Michels, Friederike, Lühder, Fred, Schunk, Domagoj, Doldi, Philipp, Tyczynski, Bartosz, Kribben, Andreas, Flüh, Charlotte, Theilig, Franziska, Kunzendorf, Ulrich, Meier, Pascal, Krautwald, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712602/
https://ncbi.nlm.nih.gov/pubmed/33273695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00690-y
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