Downregulating hypoxia‐inducible factor‐2α improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma

The hypoxic microenvironment inside solid tumors, including hepatocellular carcinoma (HCC), is a major cause of tumor resistance to chemotherapy. The recently identified hypoxia‐inducible factor (HIF)‐2 executes the hypoxia response. Its expression feature and transcriptional targets indicate a poss...

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Vydáno v:Cancer Sci
Hlavní autoři: He, Changjun, Sun, Xue‐Pu, Qiao, Haiquan, Jiang, Xian, Wang, Dongdong, Jin, Xiangguo, Dong, Xuesong, Wang, Jizhou, Jiang, Hongchi, Sun, Xueying
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712417/
https://ncbi.nlm.nih.gov/pubmed/22145922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02177.x
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