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Priming with Recombinant BCG Expressing HTI Enhances the Magnitude and Breadth of the T-Cell Immune Responses Elicited by MVA.HTI in BALB/c Mice

The use of Mycobacterium bovis bacillus Calmette–Guérin (BCG) as a live vaccine vehicle is a promising approach for HIV-1-specific T-cell induction. In this study, we used recombinant BCG expressing HIVACAT T-cell immunogen (HTI), BCG.HTI(2auxo.int). BALB/c mice immunization with BCG.HTI(2auxo.int)...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Saubi, Narcís, Kilpeläinen, Athina, Eto, Yoshiki, Chen, Chun-Wei, Olvera, Àlex, Hanke, Tomáš, Brander, Christian, Joseph-Munné, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712201/
https://ncbi.nlm.nih.gov/pubmed/33202884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040678
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