Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that causes loss of joint function and significantly reduces quality of life. Plasma metabolite concentrations of disease-modifying anti-rheumatic drugs (DMARDs) can influence treatment efficacy and toxicity. This study explored the...

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Veröffentlicht in:J Pers Med
Hauptverfasser: D’Cruz, Leon G., McEleney, Kevin G., Tan, Kyle B. C., Shukla, Priyank, Gardiner, Philip V., Connolly, Patricia, Conway, Caroline, Cobice, Diego, Gibson, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712198/
https://ncbi.nlm.nih.gov/pubmed/32993083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm10040149
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