Comprehensive Evaluation of Immune-Checkpoint DNA Cancer Vaccines in a Rat Cholangiocarcinoma Model

Cholangiocarcinoma (CCA) is a malignant tumor with aggressive biological behavior. Immune checkpoints such as cytotoxic T-lymphocyte antigen 4 (CTLA4) and antiprogrammed death 1 (PD-1) are critical immune-checkpoint molecules that repress T-cell activation. The DNA vaccine potential against CTLA4 an...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Pan, Yi-Ru, Wu, Chiao-En, Chen, Ming-Huang, Huang, Wen-Kuan, Shih, Hsuan-Jen, Lan, Keng-Li, Yeh, Chun-Nan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712087/
https://ncbi.nlm.nih.gov/pubmed/33255375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040703
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